Dr. Osman Salih Osman Ahmed
Assistant Professor
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osmansa@agu.edu.bh
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Dr. Osman Ahmed earned his MBBS from Khartoum University in 2006 and began his academic career as a teaching assistant in Biochemistry. He completed his internship and worked at Khartoum’s leading diabetic center (2008–2012), earning an MSc in Medical Biochemistry while teaching metabolism and treating patients. In 2012, he joined Prof. Paolo Parini’s group at Karolinska Institutet, Sweden, where his PhD research led to a patented dual inhibitor of PCSK9 and ACAT2, co-founding Lipoprotein Research Stockholm AB. He defended his thesis in May 2019 and was awarded the prestigious Novo Nordisk Postdoctoral Fellowship, studying neural control of liver inflammation and metabolism with Prof. Peder Olofsson. His postdoctoral work yielded six publications so far, including in Nature Cardiovascular Research and Journal of Internal Medicine, and an invited talk at EASL 2022. In September 2024, he was appointed Assistant Professor of Medical Biochemistry at Arabian Gulf University, Bahrain.
- Post-doctoral Fellowship in Neuro-immuno-metabolism, Karolinska Institute, Sweden, 2024
- Ph.D. in Clinical Chemistry, Karolinska Institutet-Sweden, 2019
- M.Sc in Medical Biochemistry, University of Khartoum, Sudan, 2009
- MBBS in Medicine and Surgery, University of Khartoum-Sudan, 2006
- Dyslipidemia with a focus on fatty liver, obesity and cardiometabolic disorders
- Diabetes and it’s complications
- Bioelectronic Medicine with a focus on vagus nerve and its effect on systemic metabolism
- Ahmed O, Shavva VS, Tarnawski L, Dai W, Borg F, Olofsson VV, Liu T, Saliba-Gustafsson P, Simini C, Pedrelli M, Bergman O, Norata GD, Parini P, Franco-Cereceda A, Eriksson P, Malin SG, Björck HM, Olofsson PS. Statins regulate hepatic PNPLA3 expression through a mechanism that requires SREBF2 in human hepatic cells. Journal of Internal Medicine. 2024 Nov 19. doi: 10.1111/joim.20032.
- Di Nunzio G*, Hellberg S*, Zhang Y*, Ahmed O*, Wang J, Zhang X, Björck HM, Chizh V, Schipper R, Aulin H, Francis R, Fagerberg L, Gisterå A, Metso J, Manfé V, Franco-
- Cereceda A, Eriksson P, Jauhiainen M, Hagberg C, Olofsson PS, Malin SG. Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult. Nature Cardiovascular Research, 2024 March 11; 3(3):356-371. doi: 10.1038/s44161-024-00448-6. * Contributed equally
- Ahmed O, Caravaca AS, Crespo M, Dai W, Liu T, Guo Q, Leiva M, Sabio G, Shavva VS, Malin SG, Olofsson PS. (March 2023). Hepatic stellate cell activation is regulated by the vagus nerve in systemic inflammation. Journal of Bioelectronic Medicine, 2023 Mar 31;9(1):6. doi: 10.1186/s42234-023-00108-3.
- Ahmed O, Pramfalk C, Pedrelli M, Olin M, Steffensen KR, Eriksson M and Parini P. (2019). Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice. Dig Liver Dis. 2019 Jul; 51 (7):1016-1022.
- Ahmed O*, Littmann K*, Gustafsson U, Pramfalk C, Öörni K, Larsson L, Minniti ME, Sahlin S, Camejo G, Parini P and Eriksson M. (2018). Ezetimibe in combination with simvastatin reduces remnant-cholesterol without affecting biliary lipid concentrations in gallstone patients. J Am Heart Assoc. 2018 Dec 18;7 (24):e009876. * Contributed equally.