Mohamed Ridha Barbouche
Professor of Microbiology, Immunology, and Infectious Diseases
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mohamedrb@agu.edu.bh
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البريد الإلكتروني |
| السيرة الذاتية | تحميل |
| الباحث العلمي (جوجل) |
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M.D., Ph.D., Professor of Immunology, he trained at the Pasteur Institute and at Necker Hospital in Paris, he was post-doctoral fellow at Cornell University in New York. He was the head of the Department of Immunology at the Pasteur Institute of Tunis, University of Tunis El-Manar and joined the AGU as a Professor in 2022. His clinical interests are the investigation of immune-mediated diseases, and his research activity is dedicated to the study of host-pathogen interactions. He is an external member of the Scientific Board of the International Pasteur Network. He sits as an expert in different vaccinology working groups at the WHO. He is member of the International Union of Immunological Societies Council and its Education Committee. He produced research work in Immunology, including immune deficiencies and immunity to infections with more than 135 peer-reviewed publications. His h-index is 35. He was awarded the Besrour-University of Montreal Research Prize.
- M. D., University of Tunis, 1985; Speciality in Immunology, 1990
- M. Sc. in Immunology, University Paris VI, 1992
- Ph. D. in Immunology, University Paris VI, 1995
- Basic Immunology, Host-pathogen interactions
- Host-Pathogen Interactions, Genetic susceptibility to infection
- Immune-mediated diseases, mechanisms of immune-mediated diseases
- Belghith M, Maghrebi O, Ben Laamari R, Hanachi M, Hrir S, Saied Z, Belal S, Driss A, Ben Sassi S, Boussoffara T, Barbouche MR. Increased IL-22 in cerebrospinal fluid of neuro-behçet's disease patients. Cytokine. 2024 Jul;179:156617. doi: 10.1016/j.cyto.2024.156617.
- Al-Mousa H and Barbouche MR. Genetics of Inborn Errors of Immunity in highly consanguineous Middle Eastern and North African populations. Semin Immunol. 2023 May;67:101763. doi: 10.1016/j.smim.2023.101763.
- Ben-Ali M, Ben-Khemis L, Mekki N, Yaakoubi R, Ouni R, Benabdessalem C, Ben-Mustapha I, Barbouche MR. Defective glycosylation leads to defective gp130-dependent STAT3 signaling in PGM3-deficient patients. J Allergy Clin Immunol. 2019 Apr;143(4):1638-1640.e2. doi: 10.1016/j.jaci.2018.12.987.
- Refai A, Gritli S, Barbouche MR, Essafi M. Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It to the Anti-inflammatory M2 Phenotype. Front Cell Infect Microbiol. 2018 Sep 18;8:327. doi: 10.3389/fcimb.2018.00327.
- Sassi A, Lazaroski S, Wu G, Haslam SM, Fliegauf M, Mellouli F, Patiroglu T, Unal E, Ozdemir MA, Jouhadi Z, Khadir K, Ben-Khemis L, Ben-Ali M, Ben-Mustapha I, Borchani L, Pfeifer D, Jakob T, Khemiri M, Asplund AC, Gustafsson MO, Lundin KE, Falk-Sörqvist E, Moens LN, Gungor HE, Engelhardt KR, Dziadzio M, Stauss H, Fleckenstein B, Meier R, Prayitno K, Maul-Pavicic A, Schaffer S, Rakhmanov M, Henneke P, Kraus H, Eibel H, Kölsch U, Nadifi S, Nilsson M, Bejaoui M, Schäffer AA, Smith CI, Dell A, Barbouche MR, Grimbacher B. Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels. Journal of Allergy and Clinical Immunology, Volume 133, Issue 5, 2014, Pages 1410-1419.e13, doi: org/10.1016/j.jaci.2014.02.025.